Here you'll learn all you need to know to have an informed discussion with your doctor about Rituxan® (rituximab)—a rheumatoid arthritis (RA) treatment. Rituxan is used with methotrexate to treat moderate to severe RA in adults, after another type of treatment called an anti-TNF (which stands for anti-tumor necrosis factor) hasn't worked well enough. People with serious infections should not receive Rituxan.
I DID NOT RESPOND WELL ENOUGH TO AN ANTI-TNF, NOW I’M ON RITUXAN AND IT’S WORKING FOR ME.
taking Rituxan with methotrexate to treat his RA
Results may vary
What is the most important information I should know about Rituxan?
Rituxan can cause serious side effects that can lead to death, including:
- Infusion-Related Reactions: Infusion-related reactions are the most common side effect of Rituxan treatment. Serious infusion-related reactions can happen during your infusion or within 24 hours after your infusion
- Severe Skin and Mouth Reactions: Tell your healthcare provider if you get any of these symptoms during treatment with Rituxan: painful sores or ulcers on your skin, lips, or in your mouth; blisters; peeling skin; rash; or pustules
- Hepatitis B Virus (HBV) Reactivation: If you have had hepatitis B or are a carrier of hepatitis B virus, receiving Rituxan could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems, including liver failure and death. You should not receive Rituxan if you have active hepatitis B liver disease
- Progressive Multifocal Leukoencephalopathy (PML): PML is a rare, serious brain infection caused by a virus that can happen in people who receive Rituxan. People with weakened immune systems can get PML. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML
Please see the Important Side Effect Information page and the Rituxan Prescribing Information and Medication Guide for additional Important Side Effect Information, including Most Serious Side Effects.