AFTER TAKING AN ANTI-TNF

Are you familiar with the term anti-TNFs? Anti-TNFs are among a class of rheumatoid arthritis (RA) treatments called biologics, and the name stands for anti-tumor necrosis factor. They're usually the first biologic to be given upon diagnosis with RA.* Many people have success with anti-TNFs. But if these treatments stop working well, some may decide to make a change after talking with their doctor. Sometimes those people will try another anti-TNF treatment; however, many have worked with their doctor to choose a different type of treatment, like B-cell therapy.

CONSIDER AN RA TREATMENT THAT WORKS DIFFERENTLY

Unlike anti-TNFs, B-cell therapy targets a type of white blood cell called a B-cell, which is believed to play a role in the symptoms and joint damage of RA. Currently, Rituxan® (rituximab) in combination with methotrexate is the only B-cell therapy approved to treat RA.

SERIOUS SIDE EFFECT INFORMATION

Rituxan can cause serious side effects that can lead to death, including:

  • Severe Skin and Mouth Reactions: Tell your doctor or get medical help right away if you get any of these symptoms at any time during your treatment with Rituxan:
    • Painful sores or ulcers on your skin, lips, or in your mouth
    • Blisters
    • Peeling skin
    • Rash
    • Pustules

For more information, please visit the Important Side Effect Information page.

How is Rituxan different?

Watch this video to see how Rituxan targets B-cells.

*Common anti-TNF treatments are Cimzia® (certolizumab pegol), Enbrel® (etanercept), Humira® (adalimumab), Remicade® (infliximab), and Simponi® (golimumab). All trademarks are the property of their respective owners. All treatments are prescription only.

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