RESULTS WITH RITUXAN

If you're not being helped enough by tumor necrosis factor inhibitors (TNFis, also known as anti-TNFs), and you and your doctor decide to make a change, consider some of the potential benefits of switching to Rituxan® (rituximab) in combination with methotrexate:

  • Up to 6 months of relief: Rituxan is a rheumatoid arthritis (RA) treatment that can provide up to 6 months of symptom improvement from 1 course of treatment (2 infusions given 2 weeks apart; the first infusion usually lasts 4 to 6 hours. Infusions after your first may take slightly less time, but will still last several hours). In fact, a study showed that at 6 months, 51% of the people taking Rituxan (plus methotrexate) experienced RA symptom improvement (called an ACR20 response), as opposed to 18% of people taking methotrexate alone
  • A study also showed that, of the people who saw improvement from their first course of Rituxan (plus methotrexate) and then went on to receive a second course, 54% saw an additional 6 months of improvement (as opposed to 45% of people who received methotrexate alone)
  • Rituxan dosing schedule: Rituxan is typically given every 6 months, or based on your doctor's evaluation of your symptoms (but no sooner than every 4 months). View the dosing chart
  • Helps slow the progression of joint damage: In a study, Rituxan with methotrexate was proven to slow joint damage for many patients after 1 year of treatment compared to methotrexate alone

Talk to your doctor about the results others have experienced with Rituxan, and discuss whether it may be right for you.

SERIOUS SIDE EFFECT INFORMATION

Rituxan can cause serious side effects that can lead to death, including:

  • Hepatitis B Virus (HBV) Reactivation: Before Rituxan treatment, your doctor will do blood tests to check for HBV infection. If you have had hepatitis B or are a carrier of hepatitis B virus, receiving Rituxan could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems, including liver failure, and death. You should not receive Rituxan if you have active hepatitis B liver disease. Your doctor will monitor you for hepatitis B infection during and for several months after you stop receiving Rituxan

For more information, please visit the Important Side Effect Information page.

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